Natural Competence Promotes Helicobacter pylori Chronic Infection
نویسندگان
چکیده
منابع مشابه
Natural competence promotes Helicobacter pylori chronic infection.
Animal models are important tools for studies of human disease, but developing these models is a particular challenge with regard to organisms with restricted host ranges, such as the human stomach pathogen Helicobacter pylori. In most cases, H. pylori infects the stomach for many decades before symptoms appear, distinguishing it from many bacterial pathogens that cause acute infection. To mode...
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To study whether the capability of horizontal DNA transfer is associated with metronidazole resistance in Helicobacter pylori, a total of 81 clinical isolates were tested for MICs of metronidazole (MTZ). The MIC assays were performed by using the E-test and reconfirmed by the agar dilution method. Natural competence assays were performed by transferring a chloramphenicol acetyltransferase casse...
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Since Helicobacter pylori was first isolated by Warren and Marshall in 1983, many investigators have reported that it is closely associated with gastro-duodenal diseases. Several diagnostic methods, C-urea breath tests, rapid urea test, histological exam and culture, are used for detecting H. pylori. Japanese monkey and Mongolian gerbils is the animal model that can sustain persistent colonizat...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2012
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.01042-12